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KMID : 0828520100140010042
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Journal of the Korean Geriatrics Society
2010 Volume.14 No. 1 p.42 ~ p.47
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A Case of Pseudomembranous Aspergillus Tracheobronchitis in a Patient with Diabetes Mellitus
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Yi Young-Arm
Kim Jong-Min
Hwang Se-Jin
Sung Shi-Jung
Kim Se-Jin
Kim Young-Min
Seo Kwang-Won
Ra Seung-Won
Jegal Yang-Jin
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Abstract
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Aspergillus tracheobronchitis is one form of invasive pulmonary aspergillosis which is characterized by ulcers and pseudomembrane formation in tracheobronchial tree. In Aspergillus tracheobronchitis, the infection is often limited to the mucosa and it accounts for less than 10 percents of invasive disease. Invasive aspergillosis mainly occurs in immunocompromized patients with prolonged neutropenia, advanced AIDS, organ transplantation, high-dose glucocorticoid therapy or cytotoxic therapy although it can occur in less immunocompromised patients, such as after influenza, COPD, old age, and diabetes. We report a case of Aspergillus tracheobronchitis in a 61 year-old patient with diabetes and Child Pugh class A liver cirrhosis. He presented with cough and purulent sputum for 10 days. He was diagnosed by bronchoscopy and successfully treated with antifungal therapy.
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KEYWORD
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Invasive pulmonary aspergillosis, Bronchitis, Diabetes mellitus
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